W.H.A.T.

Available positions

potentially interesting WHATERs around the world


September 2014

M. R. C. Medical Research Council

Post Doctoral Training Appt on Cancer Biology (IRC159253) Special focus: micro-RNA and metabolism.

The Medical Research Council Toxicology Unit is an internationally renowned institution delivering field-changing mechanistic insights into toxicology and disease. The scientific group led by Gerry Melino publishes extensively in high impact factor journals. We are now looking for a Post Doctoral Training Appt. to join the group working on CANCER BIOLOGY.

This is a three year training and development position suitable for a scientist who has just completed their PhD (or following a first Post-Doc fellowship) or those wishing to move into a new research discipline. Candidates should have a background and interest in apoptosis and cancer with experience of cellular and molecular biology and/or biochemistry.

Salary: 28,648 per annum.

For further information about the Toxicology Unit, the Apoptosis and Cancer group please visit: http://www.mrctox.le.ac.uk/

Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at http://www.topcareer.jobs, please upload a CV & cover letter (saving the documents with the IRC reference in the filename). If you are unable to apply online please contact us on 01793 867003. Please quote the reference number.

If you experience problems with your on-line application please contact Amanda Harris (ajh12@le.ac.uk or tel: 0116 2525581) for assistance.

Closing date for applications: October 12nd, 2014

The Medical Research Council is an Equal Opportunities Employer. Final appointments will be subject to pre-employment screening.


June 2014

A D M C & Medical Research Council Toxicology Unit

Post Doc Fellowship CANCER BIOLOGY (ref: ADMC14/06)

ADMC and the Medical Research Council Toxicology Unit, a leading research centre for cell death and mechanisms in tissue injury, invites applications from highly motivated postdoctoral scientists to join the Cancer Biology Group led by Gerry MELINO to work on projects focusing on cancer and cell death with a particular interest in the role of the p53 family in tumourigenesis, metastasis and chemo-resistance.
This is a one year (extendible up to three years) training and development position for a scientist who has completed their PhD or who wishes to move into a new research discipline.

Candidates should have a background and interest in cell death, the p53 family and/or DNA damage and/or micro-RNA.

The starting salary will be in the region of 30,000 (equivalent to circa 25,000) per annum.

For further information visit:
http://tox.mrc.ac.uk/research/melino-group/
Applications must be made by email at km179@leicester.ac.uk inputting the relevant reference (ADMC14/05) and sending: (i) CV, (ii) list of publication, (iii) one page project proposal, (v) letter of application, (vi) three reference names.
Closing date for applications is 30th June 2014


April 2013

POSTDOCTORAL POSITION ON eIF5A IN BRAZIL

The Laboratory of Molecular and Cellular Biology of Microorganisms, at the School of Pharmaceutical Sciences - UNESP in Araraquara, has a postdoctoral position (FAPESP fellowship) in the field of Molecular Biology of Saccharomyces cerevisiae. The thematic project involves mapping the site of interaction of eIF5A in the structure of the ribosome through the identification of proteins and rRNA sequence that interact physically with eIF5A by induction of "crosslinking" in vitro and using triple-hybrid system to study the interactions between eIF5A and rRNA. In addition, the project involves the study of the possible role of eIF5A in the connection between translation and secretion. Finally, the project seeks genetic interactions with eIF5A mutants using the SGA system (http://www.bv.fapesp.br/pt/projetos-tematicos/7223/controle-expressao-genica-nivel-traducional/).

This grant is linked to the thematic project 2010/50044-6, coordinated by Sandro Roberto Valentini, entitled "Control of Gene Expression at the translational level: a study of the role of eIF5A in the elongation of translation." Applicants must have a Ph.D. and experience in molecular biology techniques (gene cloning, recombinant protein production in E. coli and Saccharomyces cerevisiae, protein purification, etc.). It is necessary fluency in English, experience in bioinformatics, molecular and cellular biology of Saccharomyces cerevisiae and assays for protein-RNA physical interaction.

The successful candidate must present a documented CV with published articles that demonstrate capacity to cooperate in the development of the project and should devote himself entirely and exclusively to the project activities. In addition to conducting experiments, the postdoc will co-supervise students and engage in international collaborations and interact with other research groups in the area.

The fellowship is valued at R$ 5,578.80 (~ US$ 2,800.00) / month and lasts up to 24 months, with possibility of renewal for two additional periods of 12 months, depending on judgement of merit by FAPESP.

Applicants should send by April 20th the following documents to the e-mail:

valentsr@fcfar.unesp.br:

a) A letter of interest,
b) Curriculum vitae including a list of publications,
c) contact information (e- mail, telephone) of two professionals who can provide letters of recommendation.

******************************************************
Sandro Roberto Valentini
Professor of Molecular Biology and Microbiology
School of Pharmaceutical Sciences
So Paulo State University - UNESP
Rod. Araraquara - Jau, Km 01
ARARAQUARA - SP - BRASIL
14.801-902
Phone: +55 16 33016954
FAX: +55 16 33016940


November 2012

2-3 year Post-doctoral Position in Paris, France
09/11/2012 - 31/01/2013
A 2-3 year post-doctoral position is immediately available in the Christian Neri lab to study new mechanisms that regulate neuron resistance and survival during the early phases of the pathogenic process in Huntington's disease. Research will be focused on the use of human iPS cells and the nematode C. elegans to study interactions between neurodevelopmental and neurolongevity-promoting pathways and their effects on downstream effector mechanisms.
The project involves unbiased molecular profiling approaches complemented by mechanistic studies and benefits from excellent scientific environment and facilities.
It is require strong interest in Developmental neurobiology, Longevity/Cell-survival and Neurodegenerative disease. Significant experience in either stem cell research or C. elegans genetics, or both. Very good publication record.

Interested candidates should apply immediately

Contact : Christian Neri
christian.neri@inserm.fr
Inserm et UPMC
Inserm U894 et CNRS 7102
Biologie et Pathologie Neuronale
75005 Paris, France
Tel.: 01 40 78 86 52


July 2012

Dear Polyamine Researchers,

I am seeking a highly motivated recent PhD graduate (less than 3 years from the time of Ph.D. degree) to join our lab for post doctoral training. Our lab is trying to better understand the role of polyamines and eIF5A in mammalian cells, development and tumorigenesis.

We have two major projects: i) to investigate the role of polyamines and the mechanism of their action in mammalian cells by rapidly depleting spermidine and spermine by overexpression of SSAT1. ii) to investigate the role of eIF5A isoforms in animal tumorigenesis, using eIF5A heterozygous knock-out mice and transgenic mice over-expressing eIF5A-1 or eIF5A-2 isoforms.

The duration of NIH postdoctoral position is 2-5 years depending on the progress and the starting annual stipend is 45,000- 50,000 for a Ph.D (with less than 1 year of postdoctoral experience)and increases with experience. The start date is Oct 1 2012 and it may take up to 5 months for the final approval of the application. Those interested in joining our laboratory can find more info at the web site and contact me by e-mail.

http://www.nidcr.nih.gov/Research/NIDCRLaboratories/OralPharyngeal/MyungHeePark.htm

Thank you very much for your attention,

Myung Hee Park
301-496-5056
mhpark@nih.gov


February 2012

A 3 years PhD position is available at Covalab-France to work on the development of novel specific inhibitors to tissue transglutaminase and related tests in the framework of TRANSPATH (Transglutaminase in disease: a novel therapeutic target) a FP7 Marie Curie Initial Training Networks (ITN) project.

For more details:
http://ec.europa.eu/euraxess/index.cfm/jobs/jobDetails/33760145


Research Fellow MOLECULAR BIOLOGIST

A Postdoctoral position is available from December 01, for 2 years within the framework of the Marie Curie Seventh Framework Programme Industry-Academia Partnerships and Pathways (IAPP) The Commercialisation of Transglutaminase (TRANSCOM PIA-GA-2009-251506) at the University of Debrecen. The successful candidate will work in the Department of Biochemistry and Molecular Biology within a team of experts in the field of transglutaminases under the supervision of Prof Lszl FssM and Dr. Robert Kirly. The TRANSCOM network involves 6 other partners and the successful candidate will be involved with other members of the network, and will attend network courses, meetings and workshops and may be involved in spending short periods of time in partner laboratories.

For details see: here


Phd-student in neuroscience

Job description

Project Title: Tissue Transglutaminase in astrogliosis and oligodendrocyte differentiation: towards improved remyelination

For more information, click here


Research Associate / Post-doctoral fellow

Published on this web page on 1/03/2010

Research Associate / Post-doctoral fellow
Reference: 2010/0078
Closing date: 10 March 2010
Salary: GBP 28983 - 35646 per annum (Grade 6)
for details see: http://www.cf.ac.uk/jobs/index.html, academic positions, reference 2010-0078

The Cardiff research group together with the Centre for Ataxia at the Sheffield Hallamshire Hospital, invite applications from highly motivated scientists to join the research team to investigate the mechanism leading to neurological dysfunction in a subset of patients with gluten sensitivity. The research project funded by Coeliac UK is entitled Transglutaminase 6 autoantibodies: A novel diagnostic marker for neurological manifestations of gluten sensitivity. We are looking for a scientist who has completed or is in the process of completing his/her PhD and has an interest in immune-mediated diseases.


Postdoctoral Fellow and Research Associate - Boston University School of Medicine

Published on this web page on 10/02/2010

Department: Physiology and Biophysics
Location: Boston, Mass
URL: biophysics.bumc.bu.edu/faculty/guo/index.html
Start Date: immediately
Duration: 1-3 years
Description: Two positions (one postdoctoral fellow and one research associate) are open for highly motivated individuals to work on biochemical and crystallographic studies of enzymes involved in post-translational processings and immunity. Some crystals are already available. The work may involve any aspect of protein purification, mutagenesis, crystal growth, data collection, model building and refinement. Suitable candidates will also have the chance to participate in the biochemical characterization of the proteins. A background in protein expression/biochemistry and/or x-ray structure determination is prerequisite. Experienced macromolecular crystallographers are preferred, but highly motivated recent graduates (PhD or BS/MS degree) with a strong background in protein biochemistry and interested in learning crystallography are also encouraged to apply. The laboratory is fully equipped for biochemical experiments, and with state-of-the-art crystallographic facilities. In addition, the National Synchrotron Light Source at the Brookhaven National Laboratory is only 4-hour driving away. Available immediately, applications will be accepted till positions filled.
Other details: Equal Opportunity Employer
Please submit: Cover letter with curriculum vita and the names and addresses (including e-mail addresses) of three referees
Person to contact: Dr. Hwai-Chen Guo
Surface mail address: 700 Albany Street, Boston, MA 02118
Email address: hcguo@bu.edu
Phone number: 617-638-4023
Job Posted: 03/27/09
Job ID Number: 1238179448


Post doctoral position in enzyme characterization

Published on this web page on 10/02/2010

Application deadline
Earliest: February 1, 2010 (negotiable)
Full-time
Job refernce "MOW-3"
Geneva
For further details: http://www.isb-sib.ch/about-sib/jobs/details/151-postdoctoral.html


Postdoctoral positions are available in the Cell Biology and Biophysics Unit at the National Institute of Neurological Disorders and Stroke headed by Dr. Antonina Roll-Mecak

Entry ID: PD-4675
Postdoctoral positions are available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institute of Neurological Disorders and Stroke. The Roll-Mecak lab combines biophysical and cell biological approaches to understand the mechanism underlying intracellular organization and movement, with a focus on the microtubule cytoskeleton. Our lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda.
The NIH has a long tradition of research excellence in cytoskeletal biology and offers a stimulating environment for postdoctoral fellows interested in interdisciplinary training in cell biology and biophysics. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF, and confocal microscopes. For more information, please visit http://intra.ninds.nih.gov/rm_lab/
The position will be fully funded by the NIH. We are looking for candidates who wish to work on challenging mechanistic problems related to the microtubule cytoskeleton and have a strong background in molecular biology, biochemistry and enzyme kinetics. The lab offers excellent training opportunities in structural biology, motor biophysics, and imaging.
Candidates should preferably have less than 4 years of postdoctoral experience. To apply, please send a CV, a one-page research experience summary, and contact information of three references to Antonina@mail.nih.gov. Please write "Postdoctoral application" in the subject header.


Apoptosis Gene Regulation in Cancer
Dr. King Kwong
Entry ID: PD-4369

Published on this web page on 10/02/2010

We are looking for a highly motivated individual to join our laboratory team to investigate gene regulation of apoptosis and to develop novel treatments which target the apoptosis pathways in cancer. Our laboratory has a focus on chest malignancies such as lung cancer, esophageal cancer, and pleural mesothelioma. Applicants should possess a Ph.D., M.D./Ph.D., or equivalent degree. The position involves the ability to discuss scientific data and strategy with diverse members of the team and with collaborators, so fluency in the English language is required. Candidates must have an excellent understanding of cancer biology, molecular biology techniques, and small animal models. A detailed knowledge of how to design and perform scientific work independently and collaboratively is a must. Prior experience in gene regulation and cloning, molecular laboratory-based cancer research, and previous work in the field of apoptosis is desirable. The successful candidate may need to complete an on-site interview process and deliver a brief research presentation.

Location: NCI -- Clinical Research Center -- Bethesda.

The appointment duration is up to 5 years. Stipends are commensurate with education and experience.

Please contact:
King F. Kwong, M.D.
Principal Investigator
National Cancer Institute
CRC Room 3-3940
Bethesda, MD 20892
Phone: (301) 435-7504
Fax: (301) 451-6934
E-mail: kwongk2@mail.nih.gov


Postdoctoral Scientist position available at UCSD in San Diego, California

Published on this web page on 14/01/2009

Postdoctoral Scientist position available at UCSD in San Diego, California for research in the role of transglutaminases and their substrates in skeletal biology and skeletal diseases. Please send resume and names of references to Dr. Robert Terkeltaub, Professor of Medicine, UCSD at rterkeltaub@ucsd.edu.


JobsDB Ref.: JDBS128841201

Singapore Eye Research Institute (SERI) plays a national role in performing visual research in Singapore. We conduct clinical, applied and basic research in ophthalmology and the visual sciences in collaboration with academic, governmental, commercial, pharmaceutical and private institutes at a global level. Our focus areas of research include myopia, ocular stem cell research, ocular surface disease, diabetic eye disease and glaucoma. SERI has a close relationship with the Singapore National Eye Center.

We are inviting suitably qualified candidates for the position of:

Research Officer (Investigation of Transglutaminase) Post Date: 31 Dec 08

The successful candidate will perform experiments using techniques such as micro array, real-time PCR, genotyping, gel electrophoresis, ELISA, protein kinase activity and other protein work. You will be required to review and analyze results and maintain experiment records. You will also be responsible in all aspects of laboratory maintenance and organization, which includes the procurement of laboratory equipment and supplies.

Job Requirements:
- Degree in Molecular Biology or related course with 2-3 years relevant experience
- Meticulous with strong analytical and computer skills
- Strong interest in research work
Excellent verbal, written communication and presentation skills

Interested applicants are invited to write or email to us your personal particulars and career history, current and expected salaries together with contact number(s)

before 30 January 2009 to:
Singapore Eye Research Institute
11 Third Hospital Avenue #05-00
Singapore 168751
Email : hr@seri.com.sg


University of Glasgow

Faculty of Biomedical & Life Sciences
Division of Integrated Biology
Neuroscience and Molecular Pharmacology Research Theme

Research Assistant/Research Associate
Ref: 14787/DPO/A3
Salary: 25,623 28,839 (grade 6)/31,513 35,469 (grade 7) per annum

The Faculty of Biomedical and Life Sciences within the University of Glasgow will be initiating an innovative research programme in the field of the Ubiquitin Proteasome System (UPS). The Glasgow team will be part of an international programme funded and directed by ITI Life Sciences aimed at developing technologies to identify and validate new UPS targets implicated in disease, with a primary aim of generating new agents to treat cancer and inflammatory disorders. The postholders will form a new unit within the laboratory of Dr George Baillie and will use cutting-edge technology to investigate novel post-translational modifications implicated in disease initiation and progression.

For Further Information please visit http://www.glasgow.ac.uk/vacancies

Applications for the Research Assistant/Research Associate post should be sent to FBLS Staffing Office, West Medical Building, University of Glasgow, Glasgow, G12 8QQ, UK quoting the reference number: 14787/DPO/A3
Application forms for the Technician post should be submitted to the Human Resources Department (Recruitment Section), University of Glasgow, GLASGOW G12 8QQ quoting the reference number.

Closing date: 9th January 2009


CRCIL, Paris

A Position for a Postdoctoral Research Fellow, at CRCIL, Paris, in a field related to crosslinking reactions by tissue transglutaminase: see details at the URL: http://www.feps.org/default.asp?contentID=59

Medical College of Georgia

Apply online!

Research Assistant-Basic Science: IMMAG, PB001552-00007393
Minimum qualifications:
Associates degree from an accredited college or university in a relevant field with three years of related work experience; background in Biology or Chemistry; ability to accurately follow directions/protocol; manual dexterity required to perform experiments; willingness/ability to work with small animals.
Preferred:
Bachelors Degree from an accredited college or university in a related science field; experience with tissue culture and animal handling; computer knowledge.
Responsibilities:
This position will be responsible for the maintenance of the mouse breeding colony. The duties include, but are not limited to, performing experiments; responsibility for the preparation/culture of cell lines and primary cultures; preparing all media and reagents; maintaining the mouse breeding colony; mouse husbandry/surgery; utilizing techniques of radioimmunoassay, western analysis, transglutaminase assays, DNA synthesis assays, polyacrylamide gel electrophoresis, northern blotting, and protein, enzyme and lipids assays; organize/analyze experiment results; perform survival surgery on mice and monitor wound healing through photography.
Shift: Days/M-F/Approximately 24 hrs/wk. Minimum salary $11.60/hr. This position is support by grant funds.


Postdoctoral Position in Molecular Parasitology at UCLA

A postdoctoral position is available starting Fall of 2004 in the Department of Microbiology, Immunology and Molecular Genetics at UCLA. Our laboratory studies the organization and replication of a novel form of mitochondrial DNA (kinetoplast DNA or kDNA) in the kinetoplastid protozoa Crithidia fasciculata and Trypanosoma brucei. Our research utilizes genomic and proteomic approaches as well as biochemical, immunological and molecular genetic approaches to identify genes and proteins involved in kinetoplast DNA replication and their roles in kDNA replication and the segregation of kDNA networks. Our laboratory is part of a vibrant group of molecular parasitologists at UCLA where six laboratories address fundamental questions in the biology of a wide range of parasites. Close interaction and collaboration of the various laboratories provides an excellent training environment for postdoctoral researchers and students. Research requires a background in biochemistry or molecular biology. Prior research experience with trypanosomes is desired but not required.

I would be happy to meet with applicants during the 2004 Molecular Parasitology Meeting. Our recent work is being presented at the meeting by Krishna Murari Sinha, a postdoctoral fellow.

Send curriculum vitae and the names of three references to:

Dr. Dan S. Ray
Molecular Biology Institute and
Department of Microbiology, Immunology and Molecular Genetics
UCLA, Los Angeles, CA
90095-1570
E-mail: danray@ucla.edu


MALARIA BIOCHEMISTRY AND GENOMICS
RATHOD LABORATORY
Department of Chemistry, University of Washington, Seattle (USA)

Applications are invited from post-doctoral candidates with an interest in protein chemistry, DNA-protein interactions, RNA-protein interactions, genetic transformation of Plasmodium, and/or DNA microarrays. Prior experience in these areas is desirable but not essential. Above all, we seek well-trained, clear-thinking candidates with enthusiasm for novel scientific questions and a record of productivity appropriate for their career-stage.

Our laboratory studies the molecular underpinnings of successful antimalarial drugs and their targets, and also the nature of mutagenesis in Plasmodium falciparum. It provides excellent opportunities to learn and practice multidisciplinary science. Currently, the lab has synthetic chemists, a computer scientist, molecular biologists, and geneticists. In addition, we work closely with labs that specialize in Mass Spectrometry, X-ray and NMR-based structure determination, microfluidics, and functional genomics.
(http://depts.washington.edu/chemfac/rathod.html).

The University of Washington and related institutions offer a growing parasitology community that is unusually interactive.

The University of Washington and related institutions offer a growing parasitology community that is unusually interactive. http://www.washington.edu/index.html
http://www.sbri.org/Home/
http://depts.washington.edu/sgpp/
http://depts.washington.edu/keckcmp/
http://depts.washington.edu/pathobio/
Seattle, WA is one of the enjoyable cities in the US.
http://www.seeseattle.org/visitors/gallery.asp
For full consideration, please e-mail your application with a current CV and a list of three references to rathod@chem.washington.edu.


Research Positions in Plasmodium biology, University of Wuerzburg (Germany)

At the Research Center for Infectious Diseases (ZINF) of the University of Wuerzburg, Germany, we are currently seeking applicants for the following positions:

Postdoctoral Position (BAT IIa)
Ph.D. Student Position (BAT IIa/2)

Positions are available to study the biology of the human malaria pathogen Plasmodium falciparum, in particular the molecular and cellular interactions of the parasite during sexual reproduction and development in the mosquito vector. The postdoctoral and Ph.D. student positions require a Ph.D. and bachelor's degree (Diplom), respectively, as well as a strong background in biochemistry, molecular and cell biology. Positions will start from March 1, 2005.

I would be happy to meet with interested applicants during the 2004 Molecular Parasitology Meeting. For further information about the ZINF, please visit the website: www.uni-wuerzburg.de/infektionsbiologie/index.htm

Interested applicants please send curriculum vitae and contact information of two references to:

Dr. Gabriele Pradel
gap2002@med.cornell.edu


Postdoctoral Position at NYU, Department of Med & Mol Parasitology
Interaction Between Malaria Sporozoites and Liver Cells

Before infecting hepatocytes in the liver, their initial site of replication in the mammalian host, Plasmodium sporozoites must traverse the layer of sinusoidal cells, composed of endothelia and Kupffer cells. Recent work has shown that sporozoites attach to and enter Kupffer cells, but not sinusoidal endothelia. The parasites invade Kupffer cells in an active process and become enclosed in a vacuole that does not fuse with lysosomes. The parasites then exit the Kupffer cells and migrate through several hepatocytes before eventually settling down in a final one for multiplication and differentiation to merozoites. For more information, see: Frevert, U (2004) Trends in Parasitology 20 (9), 417-424.

The project involves the analysis of interactions between molecules expressed on the surface of the parasites and purified liver cells and mechanisms of intracellular communication between parasite and host. The successful candidate will have experience in parasitology or microbiology and microscopical techniques.

Qualifications: PhD with training in parasitology, microbiology, biomedical sciences or related discipline is required. Preference will be given to applicants with expertise in macrophage biology/immunology and confocal microscopy. Experience with electron microscopical techniques is desired, but not obligatory. The successful candidate will have the opportunity of working in a strong department with well-equipped core facilities. The position is available as of October 1, 2004.

Interested candidates should send a CV and the names and contact information of three references to:

Ute Frevert, DVM, PhD
NYU School of Medicine
Department of Medical & Molecular Parasitology
341 E 25 St
New York, NY 10010
Tel: 212-263-6755
FAX: 212-263-6637
Email: ute.frevert@med.nyu.edu


Protein Biochemist - Cambridge, Massachusetts (USA)

Position type: Full time
Job code: 04-0010
Required education: Bachelor's Degree

Infinity is seeking a Protein Biochemist to join the Cancer Cell Biology group. The ideal candidate would have extensive experience in protein expression and purification from a wide variety of sources, including E. coli, insect cells, yeasts, and mammalian cells. The Protein Biochemist will be purifying tagged, native, and multi-protein complexes. This is a key position that will provide the individual with opportunity for growth in a stimulating environment.

Requirements

- BS/MS with at least 5 years of experience, or PhD with at least 2 years of experience (including postdoc)
- Experience utilizing an FPLC system (or equivalent) with a variety of column chromatography techniques
- Proficiency with SDS gels, Western blotting, and ELISAs
- Experience with protein concentration determinations, IP of protein complexes, protein refolding, and enzyme assays
- Expertise in protein purification from bacteria, yeast, baculovirus-infected insect cells, and mammalian tissue
- Immunology and tissue culture experience are preferred

PLEASE APPLY ONLINE AT HTTP://WWW.IPI.COM/CAREERS.HTML


Postdoctoral Scientist - Mayo Clinic, Rochester, MN, USA

Description: A postdoctoral scientist position is available for a PhD in the field of Developmental Biology, Biochemistry, Cell Biology, Genetics and Molecular Biology to study RAS signal transduction in Drosophila Eye, Mammalian Cells or/and Animal Models. (1) Extensive expertise in Drosophila forward and reverse genetics, microinjection and microdissection, mutant characterization, biochemistry and molecular biology is required for this position. (2) A strong background and considerable experiences in protein purification, protein-protein interaction and immunoprecipitation and siRNA-based technique is also required for this position. Highly motivated, talented, hard-working and energetic candidates with additional experiences in gene therapy and animal models are encouraged to apply. Successful applicants must have good publication records and can demonstrate his/her creativity, expertise and productivity in the areas specified. Applications, including curriculum vita and bibliography, summary of past accomplishments, reprints of publications and the names of three references, should be sent to:

Amy Tang
Assistant Professor
Transplantation Biology Division and
Department of Biochemistry and Molecular Biology
Medical Sciences Bldg. 2-85, 200 First Street SW
Mayo Clinic College of Medicine
Rochester, Minnesota, 55905, USA
Tel 507-538-0313/Fax 507-284-4957
tang.amy@mayo.edu


Postdoctoral Position in Enzymology

Rice University, Houston, TX

A postdoctoral position is available to investigate novel proteins required for antibiotic biosynthesis in Streptomyces. Experience in recombinant protein techniques, assay development, site-directed mutagenesis, and enzyme kinetics preferred. Send CV and names of three references to: Dr. R. J. Parry, Dept. of Chemistry MS-60, Rice University, 6100 Main St., Houston, TX 77005-1892 or e-mail: parry@rice.edu.


Assistant or Associate Professor of Chemistry

The Department of Chemistry at the University of Nebraska-Lincoln (UNL) invites applications for a tenure-track or tenured faculty position at the rank of assistant or associate professor. We will add a number of faculty members as part of campus-wide enhancements in structural biology/proteomics and nanotechnology and are particularly interested in applicants with research interests in analytical/bioanalytical chemistry, materials science (inorganic or physical), or protein/macromolecular crystallography. Information about the department can be found at www.chem.unl.edu. All applicants should have a demonstrated research record; the potential for establishing and/or maintaining a significant externally funded research program, and strong interests in undergraduate and graduate teaching. Interested candidates should submit a curriculum vitae, a list of publications, the names of three references, and a succinct statement of research interests; applicants for assistant professor should also arrange to have three letters of reference forwarded. All materials should be sent to: Search Committee Chair, Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304 (Fax: 402-472-2044; e-mail: lgalusha2@unl.edu). Review of applications will begin on January 15, 2004 and the search will continue until the position is filled. The University of Nebraska is committed to a pluralistic campus community through affirmative action and equal opportunity and is responsive to the needs of dual career couples.

We assure reasonable accommodation under the Americans with Disabilities Act

Contact Ms. Leann Galusha (402-472-3634 or lgalusha2@unl.edu) for assistance.

Hideaki Moriyama
29B Hamilton Hall, Chemistry, UNL, Lincoln, NE 68588-0304
Office 402-472-5367 Dept. fax 402-472-9402
Wet Lab (HAH 405) 472-4145
Dry Lab (Str. Biol. Cor. Faci.; HAH33) 472-2883
e-mail hmoriyama2@unl.edu


TWO POSTDOCTORAL POSITIONS

Structural Proteomics in Signal Transduction
Institute of Interdisciplinary Research (I.R.I.B.H.M.), Free University of Brussels, Brussels, Belgium.
ELIGIBILITY:Ph.D. with strong background in protein research.
Duration: Two (to three) years.
Please send a detailed CV with names and addresses of two referees, and a brief summary of research plans and accomplishments to:

Dr. David Communi
I.R.I.B.H.M., School of Medicine, Campus Erasme, Bldg. C Free University of Brussels.
808, route de Lennik, B-1070 Brussels, Belgium, Europe.
Office phone: 32 2 555.4150
Laboratory phone: 32 2 555.4221/4154
Fax: 32 2 555.4655
Email: dcommuni@ulb.ac.be
http://www.ulb.ac.be/medecine/iribhm


Lecturer in Cell & Molecular Biology / Lecturer in Protein Biophysics

University of Wales College of Medicine

Department of Dental Health and Biological Sciences

Matrix Biology & Tissue Repair Research Unit

We are looking for a highly qualified molecular biologist and physical chemist to complement and build on our existing research programmes in extracellular matrix biology and tissue engineering. You will be expected to manage a research team and provide leadership in the strategic planning and management of research activities, compete for extramural funding, train graduate students, and to a limited extent participate in the undergraduate teaching course.

This position will offer excellent, newly refurbished laboratory facilities, access to state-of-the-art equipment, internationally competitive research environment and excellent quality of life.

For further details see www.uwcm.ac.uk/study/dentistry/bds

An application pack (quoting reference number DDDB210-1063) is available from the Personnel Department: telephone +44-29-2074 5110; e-mail UWCM_PERS@cardiff.ac.uk; web site www.uwcm.ac.uk/jobs .

Closing date for applications: January 16, 2004.


Research Associate

Beth Israel Deaconess Medical Center
Harvard Medical School

Department: Division of Haemostasis and Thrombosis Research
Location: Boston, MA, USA
Start Date: immediately
Duration: 3 years

Description: A NIH-funded postdoctoral position is immediately available to determine crystal structures of hematology-related proteins, including urokinase receptor, which is also a potential target for anti-cancer metastasis. Expression, purification, and crystallization protocols for urokinase receptor have been established. The Division of Haemostasis and Thrombosis Research at Beth Israel Deaconess Medical Center, Harvard Medical School, has a dynamic research environment, employing multi-discipline approaches to the study of blood coagulation and vascular biology. Applicants must have a PhD degree and, preferably, have some experience in protein purification and protein X-ray crystallography.

Please submit: CV, 3 references
Person to contact: M Huang
Surface mail address: BIDMC, RE317, 330 Brookline Ave., Boston, MA 02215
Email address: mhuang1@caregroup.harvard.edu
Fax number: 617-975-5505


Postdoctoral fellow

Cleveland Clinic Foundation
Department: Center for Structural Biology and Department of Molecular Cardiology
Location: Cleveland, Ohio, USA
URL: www.lerner.ccf.org/structbio/
Start Date: immediately, flexible

Description: A postdoctoral position in protein crystallography is available in the Center for Structural Biology and the Department of Molecular Cardiology of the Cleveland Clinic Foundation. The successful applicant will have the opportunity to be involved in several projects focused on prion proteins and/or blood clotting proteins. The laboratory is fully equipped for molecular biology, biochemistry, and experimental and computational crystallography. Applicants should hold a Ph.D. in biochemistry, chemistry, or a related field. Experienced macromolecular crystallographers are preferred, but highly motivated recent Ph.D. graduates with a strong background in protein biochemistry and interested in expanding into crystallographic work will also be seriously considered. Applicants should send a cover letter describing research experience and interests, c.v., and contact information for three references (email preferred). The Cleveland Clinic Foundation is an Equal Opportunity/Affirmative Action Employer. In addition to internationally-recognized clinical practices, it houses over 100 basic research groups. Cleveland is a very comfortable city with reasonable cost of living, easy commute, and access to excellent health care facilities and cultural institutions.

Please submit: cover letter, c.v., contact info for 3 references
Person to contact: Vivien Yee
Surface mail address: Department of Molecular Cardiology, Cleveland
Clinic Foundation, 9500 Euclid Avenue/NB20, Cleveland, Ohio, USA 44195
Email address: yeev@ccf.org
Phone number: 1(216)444-2057
Fax number: 1(216)445-1466


Postdoctoral position to work on transglutaminase (TG2)-related project

The project involves basic understanding of TG2 interaction with other proteins and significance of such interaction in conferring drug-resistance and metastatic phenotype in cancer cells. A strong background in biochemistry/molecular biology is desirable.

For consideration, please send CV and 3 letters of references to:

Kapil Mehta, Ph.D.
Division of Cancer Medicine - Box 422
UT M.D. Anderson Cancer Center
1515 Holcombe Blvd.
Houston, TX 77030, USA
Ph (713) 792-8140
e-mail: kmehta@mdanderson.org


Two Postdoctoral Scientists in the area of apoptosis and cancer (Ref: GM2002)

The Medical Research Council Toxicology Unit, under the directorship of Prof. Pierluigi Nicotera is an internationally renowned institution that has recently redirected its research thrust towards the identification of the mechanisms underlying stereotypic responses to injury. The Unit is composed of independent research groups and has state-of-the-art imaging technology (i.e., multiphoton and conventional confocal microscopy, electron microscopy), FACS, DNA microarray analysis, transgenic animal facilities, and a newly developed proteomics facility.

We are now looking to recruit two highly motivated postdoctoral scientists to join a newly established group led by Professor Gerry MELINO and Dr. Vincenzo DE LAURENZI in the area of apoptosis and cancer to work on the gene families which are at the cross-roads between proliferation and cell death (i.e. p73 gene family). These are full time positions available for 3 years with a competitive salary, access to an occupational pension scheme and 30 days holiday per year. Applicants should have a PhD in biological sciences with knowledge of molecular and cell biology.

Please send your application, together with a CV, and the name and contact details of three referees to:

Ms. Amanda Harris, MRC Toxicology
Unit, Hodgkin Building, Leicester University, Lancaster Road, P.O. Box 138, Leicester LE1 9HN U.K.
e-mail: ajh12@le.ac.uk
Closing date for applications is: January 2nd, 2003.
The MRC is an equal opportunities employer.
'Leading Science for Better Health'


Post-doctoral associate, University of Nebraska - Lincoln

Department: Biochemistry
Location: Lincoln, NE
Start Date: November 1 or later

Description: A post-doctoral position in protein crystallography is available within the University of Nebraska-Lincoln Redox Biology Center (RBC). The RBC is a Center for Biomedical Research Excellence recently established with a $10 million grant from the National Institutes of Health. The center links scientists at UNL and the University of Nebraska Medical Center conducting interdisciplinary research in redox biology, an exciting field of research with applications in the study and treatment of heart disease, cancer, cataracts and aging. As part of this initiative, an x-ray crystallography facility has been established at UNL. Candidates with experience in molecular biology, protein expression, and enzymatic assays, as well as interests in protein structure/function relationships and enzymatic mechanisms, are strongly encouraged to apply. Prior experience in x-ray crystallographic techniques is desirable, but not required.

Please submit a CV and 3 letters of reference

Person to contact: Dr. Joe Barycki
Mail address: N222 Beadle Center Lincoln, NE 68588-0664
e-mail address: jbarycki2@unl.edu
Phone #: (402)472-9307
Fax #: (402)472-7842
Job Posted: 10/09/02
Job ID Number: 1034177318


Structural Biologist University of Texas

Department: Chemistry and Biochemistry
Location: Austin TX
URL: www.cm.utexas.edu/robertus/
Start Date: ASAP

Description: We are looking for a postdoctoral fellow with an interest in protein analysis, but experience in protein chemistry, enzymology, and molecular biology. One major goal is to develop systems allowing the structure-based design of antifungal enzyme inhibitors. Additional projects are also available - see web site.

Other details: Funding for one year, with possible extension based on research progress.

Please submit: CV, 3 letters of reference

Person to contact: Dr. Jon Robertus
Surface mail address: Dept. of Chem/Biochem, University of Texas, 1 University Station A5300/ Austin TX 78712
Email address: jrobertus@mail.utexas.edu
Phone #: 512/471-3175
Fax #: 512/471-8696
Job Posted: 10/10/02
Job ID Number: 1034278060


Postdoctoral / Research Associate position funded by NIH

Postdoctoral / Research Associate position funded by NIH is currently available to study the role of cell surface tissue transglutaminase in integrin-dependent cell-matrix adhesion, signaling, cell migration and tumor invasion (JCB 148: 825, 2000; JBC 276: 18415, 2001; JCS 114: 2989, 2001; Blood 98: 1567, 2001). Recent PhDs with solid experience in cell and molecular biology / biochemistry are encouraged to apply. The position is available for 3-4 years with a possibility of extension.

Salary will commensurate with degree and experience. Interested candidates should contact Dr. Alexey Belkin, The Holland Laboratory, American Red Cross, 15601 Crabbs Branch Way, Rockville, Maryland 20855, USA.

Telephone: 301-738-0725 (voice mail); Fax: 301-738-0740;

E-mail: belkina@usa.redcross.org


POSTDOCTORAL POSITION AVAILABLE IN MOLECULAR AND CELLULAR BIOLOGY

Open Until Filled. The initial appointment will be for two years, renewable thereafter.
NIH-supported research position is available immediately to study the 
role of tissue transglutaminase in the process of liver cell 
proliferation and hepatic fibrogenesis. This unique protein has two 
distinct functions: it acts as a cross-linking protein when in the 
nucleus, cytoplasm, and extracellular space, and it functions as a g-
protein when in the cell membrane. Thus, it can either enhance 
apoptosis or increase cell proliferation. The work to be undertaken is 
based on our publication, JBC 2000, 275: 22213-22219. It will entail 
both in vitro and in vivo studies involving gene transduction 
experiments, work with a knock-out model that is already available, as 
well as a series of studies dealing with second messenger signaling. In 
addition to this project, the person taking the position will have the 
opportunity to take part in other studies presently ongoing in the lab, 
including: the immortalization of hepatocytes and the development of a 
bioartificial organ, gene therapy of alpha 1-antitrypsin deficiency, 
and the targeting of therapeutics to the liver. Our work entails a 
close interaction with the Medical Technology Program at Lawrence 
Livermore National Laboratory. 

Salary is commensurate with degree and experience. Please forward a letter of interest, CV, and e-mail addresses and phone numbers of 3 references to Professor Mark Zern.

Dr. Mark A. Zern Director, Transplant Research Institute 4635 2nd Avenue, Room 1001 Sacramento, CA 95817 Phone: 916-734-8063 FAX: 916-734-8097 mazern@ucdavis.edu http://gradstudies.ucdavis.edu/postdocs/employment.htm


1 post-doctoral and 1 project leader positions immediately available in basic and applied skin biology.

Research experience in morphological and cell/tissue culture techniques required.
Background in developmental biology, skin research and/or pharmacology preferred.
Focus: hair research; see publications R Paus (PubMed etc.).
Net salary: 20.000-30.000 Euro/year
Location: 2001-09/2002 Hamburg (Germany), starting from 10/2002 Trieste (Italy).
For questions/further details, contact:
Dr. Paolo Pertile, Cutech Srl, Padova, Italy
Email: ppert@iol.it


Postdoctoral Fellow
Cold Spring Habor Laboratory
Location: Long Island, New York
URL: http://www.cshl.org/
Start Date: immediately
Duration: 3 years
Description: Applications are invited for a postdoctoral position in Structural Biology at Cold Spring Harbor Laboratory to work on complexes involved in apoptosis or gene expression. The positions are available for highly motivated applicants with a recent Ph. D. and experience in either protein crystallography or a related field or those with experience in biochemistry or molecular biology and a keen interest in protein crystallography and structural biology. Experience in protein expression and purification is an advantage. Our X-ray crystallography facilities include a Rigaku generator, mirrors, an R-axis detector, an Oxford cryosystem and several graphics workstations. We share a beamline at the nearby National Synchrotron Light Source (NSLS) at Brookhaven. We also have state-of-the-art facilities for carrying out biochemical and molecular biology studies. Cold Spring Harbor provides a unique stimulating and very collaborative environment for rich scientific interactions. It is a wonderful place to expand ones knowledge of biology in many different areas with the many meetings that our postdocs can freely attend. For details about CSHL please see our web site at: http://www.cshl.org/ Please send CV, list of publications, a summary of research experience and interests, and names and numbers of three references to Dr. Leemor Joshua-Tor, Cold Spring Harbor Laboratory, P. O. Box 100, Cold Spring Harbor, NY 11724. Tel. (516) 367 8821. For additional information or informal inquiries, please send e-mail to leemor@cshl.org

Please submit: CV, names of references
Person to contact: Leemor Joshua-Tor
Surface mail address: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Email address: leemor@cshl.org
Phone number: 516-367-8821
Fax number: 516-367-8873
Job Posted: 05/14/01


Postdoctoral Fellow

Cleveland Clinic Foundation

Department: Molecular Cardiology, Lerner Research Institute
Location: Cleveland, Ohio, USA
Start Date: Immediately
Description:
Two postdoctoral positions in protein crystallography are available in the Department of Molecular Cardiology at the Lerner Research Institute of the Cleveland Clinic Foundation. Applicants should hold a Ph.D. in biochemistry, chemistry, or a related field; prior experience in macromolecular crystallography or in molecular biology and protein expression/purification is required. Projects available include blood coagulation proteins and a multienzyme complex. Diffracting crystals of some of the proteins have been obtained, and there is the opportunity to carry out structure determination by either heavy atom phasing methods or by molecular replacement. The laboratory is fully equipped for protein expression and purification, and macromolecular crystallography. Our group is one of several structural biology research labs in the Lerner Research Institute, which houses over 100 independent laboratories and is the research arm of the renowned Cleveland Clinic Foundation. These postdoctoral positions are available immediately and supported by external funding for up to five years; applications will be accepted until the positions are filled. Experienced macromolecular crystallographers, or molecular biologists/protein chemists interested in expanding into crystallographic work, will be seriously considered. Salary will be competitive and commensurate with qualifications and experience. Highly qualified candidates can also be considered for institutional fellowships which provide for salary supplementation.
Other details: The Cleveland Clinic Foundation is an Equal Opportunity/Affirmative Action Employer.
Please submit: CV, names of 3 references, cover letter
Person to contact: Vivien Yee
Surface mail address: 9500 Euclid Avenue/NB20, Cleveland, OH, USA 44195
Email address: yee@pierre.lerner.ccf.org
Phone number: 1 (216) 444-2057
Fax number: 1 (216) 445-1466
Job Posted: 05/26/00
Job ID Number: 959351515 ********************

Postdoctoral Position in Structural Biology

 

Center for Macromolecular Crystallography

Location: University of Alabama at Birmingham

URL: http://www.cmc.uab.edu/faculty_staff/narayana

Start Date: Summer 2001

Duration: 3 years

Description: One or two postdoctoral positions in protein crystallography are available in summer/fall of 2001 to study the structure function relationships of (a) bacterial surface proteins that bind to collagen and fibrinogen, (b) enzymes that are involved in the human complement activation, and (c) calcium regulated cystein proteases calpains and tissue transglutaminase. Good crystals are available for some of the proteins and excellent expression systems are present for all of them. In addition, the research atmosphere at University of Alabama at Birmingham is highly conducive for collaborative research and there are excellent opportunities for young investigators to participate in other ongoing projects and to initiate independent research projects. Research work in my laboratory will involve protein purification, crystallization, data collection, model building, and refinement. Outstanding research facilities are available in our center for these studies. Applicants with experience in all the aspects of macromolecular crystallography combined with high enthusiasm to do or learn molecular biology/protein biochemistry will be considered. Salary will be commensurate with experience.

Interested individuals should send their CV and three letters of recommendation to:

Dr. Narayana Sthanam, School of Optometry, 286 MCLM, University of Alabama at Birmingham, 1918

University Blvd., Birmingham, AL35294, USA.

Please submit: CV and 3 references.

Person to contact: Dr. Narayana Sthanam

Surface mail address: 286 MCLM, 1918 University Blvd, Birmingham, Al35294, USA.

Email address: narayana@pearl.cmc.uab.edu

Phone number: 205 934 0119 Fax number: 205 934 0480

Job Posted: 01/16/01

Job ID Number: 979667088

 


Postdoc. positions

Cornell University

 

Department: Chemistry and Chemical Biology

Location: Ithaca, NY

URL: http://arginine.chem.cornell.edu/index.html

Start Date: ASAP

Description: Two postdoctoral positions are available in protein crystallography at Cornell University. One position is for application of direct methods and anomalous scattering to protein structure determination. This position is in collaboration with Dr. Herbert Hauptman and involves the combination of direct methods and anomalous scattering (MAD/SAD) in protein structure determination. A wide variety of interesting proteins are available for study. The second position is for the application of protein crystallography to structure-based drug design and in the elucidation of enzyme mechanisms. Specific areas of focus include purine nucleotide metabolism, polyamine biosynthesis, and cofactor biosynthesis. We are actively collaborating with molecular modelers and medicinal chemists in both academia and in private companies. Cornell University is situated in the heart of the Finger Lakes region in Ithaca, New York, a diverse community that offers a wealth of cultural and recreational activities.

The laboratory is well-equipped with all equipment necessary for protein expression, purification and crystallization, and X-ray crystallographic analyses. Synchrotron beam time is available at the Cornell High Energy Synchrotron Source and at the Advanced Photon Source.

Other details: Cornell is an equal opportunity employer.

Please submit: Cover letter, CV, names of three references

Person to contact: Professor Steven E. Ealick

Surface mail address: Baker Laboratory, Cornell University, Ithaca, NY

14853-1301

Email address: see3@cornell.edu

Phone number: 607-255-17961

Fax number: 607-255-1227

Job Posted: 03/15/01

Job ID Number: 984675758